If so, what drives the behaviour?
Aside from alcohol, there are no drugs that I enjoy. Even with alcohol, I don't like being intoxicated. I can't even take strong prescription painkillers. I hate that groggy disconnect that I get from them.
@JimG -- That's true for many of us, maybe even a majority, but we as a species are prone not only to get hung up on various drugs, but all sorts of other psychological states of mind as well.
Like you, I don't take even over the counter stuff unless it is absolutely (heavy stress on 'absolutely' necessary. I definitely do not like that disconnect.
I would be happy to spend my life with only with one drug, Hul Gil- the Joy plant. It would be a short but happy life. Of course, that is not an option.