I of course realize that pest control has been hugely beneficial to agriculture. But I'm also very aware that pretty much every human interference carries unintended consequences -- sometimes catastrophically.

From the link

As Big Ag fumed Monday over a U.S. Environmental Protection Agency determination that herbicides including the endocrine-disrupting atrazine and carcinogenic glyphosate are likely to harm more than 1,600 protected plant and animal species, environmentalists pointed to the agency's findings as proof of the need for stricter limits on the use of the dangerous poisons.