IMO the single biggest threat to the USA, and this the world are Evangelicals, Trump supporters, and far right-wing conservatives.
They are a bigger threat to climate change, as their denying and roadblocking will ultimately exacerbate and accelerate climate change.
These groups are exacerbating the situation in isreal. Their platform is that the Apocalypse is nye, and they are doing everything with their monetary support, their policy making, and their support for the present apartheid government in Isreal. They are working to actualize the the events leading up to their supposed apocalypse.
This includes the movement of the capital to Jerusalem. They attack moslems in Isreal to eventually find an excuse to tear down the mosque on the temple mound. All the while working to destroy the Palestinian peoples. (Even appointed an anti-christ in the figure in Trump-lol). They chide and create false opportunities in order instigate a situation with Iran that will destabilize and add to the apocalyptic events bring Isreal and Iran in war.
They have dismantled the EPA. They are well on their way to allowing the hydrocarbon, coal, and mining industries to destroy the environment for future genetations.
They allow large Pharma to inflate needed medicines by as much as 5000% while making it illegal for the government to negotiate reasonable costs.
This just scratching the surface. Because the US is the most affluent nation on the Esrth. Because we have a greater military footprint that almost all other countries combined. Because what our economy does affects economies all around the globe. Because for generations nations around the world looked to the US for fairness, ethical behavior and leadership, and for support, what we do matters. That is why this immoral cabal is more dangerous than any other single threat, because they cause and exacerbate them all.