At almost 80, I've seen a lot of change. Some things I will not live to see, and it pisses me off;
1 Colonization of the solar system, including robotic mining of asteroids to build ships in space.
2 Why not use hollowed-out asteroids as ships, anyway? There's no need for aerodynamics, is there? Won't see that, either.
3 Longevity treatments, alas for me.
4 Faster-than-light travel.
5 Alien relations--hopefully of the peaceful kind.
There are many more. I do not fear death, but regret that I won't be around to see what happens, and I know a lot is going to happen. I'd appreciate and additions to this list from the community.

Hope to see a man living on Mars for a few months.

The return of indentured servitude in the Anglosphere.

The end of the Orange Clown.

Donut delivery. I know it won't happen, but a man can dream.

the end of life for humans and much more.

A colony on Mars.
A true A.I.
A self powered exo-skeleton for the handicaped.

Two unrelated predictions:
We will see a redefinition of what it means to be human as new technological and bio-implants that enhance and extend life become commonplace. The gray zone that Terri Schaivo accentuated on what it means to be alive will come to the question of what it means to be human. Whether this is good or bad is debatable.

Once a practical large scale energy storage technology is found we will see a change in the economics of energy that will be as fundamental as cellphones have changed communication.

Sentencing and prison reform and the end of direct file.

Half of us will live longer than average.

The Singularity