No, just appreciate someone is interested in you.

No more than if you decline a brunette because you prefer blonds. Intimacy, at any level above coffee at McDonald's requires a level of comfort from both participants. Are some 40-50 y/o women ageist because they won't date an old fart like me? Am I agesist for not being interested in them?

No, and it has nothing to do with your sexuality. For example, gay men, being only into men, have little interest in trans women. And a straight trans woman isn't going to date another trans woman; she would only be interested in dating men.

Etc.

I'm going to be a bit graphic here, as one who considers himself heteroflexible.

I'll date anyone of any sexuality with certain caveates, and I have a female friend who feels similarly. Anal penetration, give or receive, OK. With my friend, vaginal/anal penetration give or receive, OK. Oral to penis, for me, no. Oral to vagina for her, no.

.. or ..

I think the inherant problem with your question is that it implies that trans men aren't really men and trans women aren't really women. Not wanting to date someone doesn't make you a bigot in itself, just be respectfull.

This doesnt even seem like a real question, almost trollish. You can decline a show of interest from any person.

And if a straight person shows interest & you decline, does it make you a frigid bitch/uptight asshole? Get a grip!
You know it wasn't until writing this I realized there is no derogarory term for men equivalent to "frigid bitch"!!! Discuss.........

If I show interest in a transgender or intersex person and they decline in a friendly way, does that make them a bigot, especially when they are transgender or intersex?

No

No. We all have our turn ons and turn offs and we are entitled to them. We owe no explanations for them.

no.

No. Do they know what you've been through?