What Is The Most Astounding Fact About The Universe? - Neil deGrasse Tyson...
We probably don't even know the answer to this question yet.
Our planet may be called 'Planet Hell' by other denizens of the universe. We need oxygen to survive, oxygen which corrodes metals, turning iron to rust and breaking it into smaller and smaller pieces until you are left with iron ore, and reacts to most substances. We need water also, sometimes called a unversal solvent because so many things will dissolve in it (sounds like an extreme acid or base). So we need these two substances, which are highly reactive, in order to live. ET may take a look and say WTF?
I'm reading "The Story Of Earth" by Robert M. Hazen, not finished yet, but fascinating!